Gene
dtymk
- ID
- ZDB-GENE-990603-11
- Name
- deoxythymidylate kinase (thymidylate kinase)
- Symbol
- dtymk Nomenclature History
- Previous Names
-
- tymk
- wu:fa12c02
- wu:fb14h07
- wu:ft84f02
- zgc:123174
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have nucleoside diphosphate kinase activity; thymidylate kinase activity; and uridylate kinase activity. Predicted to be involved in dTDP biosynthetic process; dTTP biosynthetic process; and dUDP biosynthetic process. Predicted to localize to cytosol; mitochondrion; and nucleus. Orthologous to human DTYMK (deoxythymidylate kinase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Vanoevelen et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodegeneration, childhood-onset, with progressive microcephaly | 619847 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | P-loop containing nucleoside triphosphate hydrolase | Thymidylate kinase | Thymidylate kinase, conserved site | Thymidylate kinase-like domain |
|---|---|---|---|---|---|
|
UniProtKB:Q3B752
|
212 |
Interactions and Pathways
No data available
Plasmids
No data available